# La Roche-Posay 0.3% Retinol + Vitamin B3 Serum

> La Roche-Posay Retinol B3 Serum, labelled 0.3% Retinol + Vitamin B3 Serum in the UK, combines 0.3% retinol with niacinamide, retinyl palmitate and hyaluronic acid. The brand directs evening use once or twice a week at first, building towards nightly, with SPF by day. It was £48 for 30ml at LOOKFANTASTIC on 25 September 2026.

- Canonical: https://thecastindex.com/beauty/la-roche-posay-retinol-b3-serum
- Category: Skin prep
- Format: Retinol serum
- Finish: Lightweight serum
- Best for: A measured first retinol routine
- Official: https://www.laroche-posay.co.uk/en_GB/retinol-b3-anti-ageing-serum-for-sensitive-skin-30ml/LRP_115.html
- Reviewed: 2026-09-25
- Method: evidence-led desk review of official specifications — not an implied hands-on test

## Should you buy this?

A measured first retinol at 0.3%, with niacinamide and a gradual schedule on the pack, at £48. It suits a cautious start — but it contains fragrance and denatured alcohol despite the sensitive-skin positioning.

Skip this if you want a fragrance-free retinoid, are pregnant or breastfeeding, or already tolerate a stronger retinoid.

A measured evening retinol at the 0.3% level — a night-routine treatment, kept apart from daytime base.

## The formula

La Roche-Posay’s Retinol B3 Serum, labelled in the UK as 0.3% Retinol + Vitamin B3 Serum, combines retinol at 0.3% with niacinamide, retinyl palmitate and hyaluronic acid in a lightweight dropper serum. The brand positions its range for sensitive skin.

The 0.3% figure also matches the maximum retinol equivalent the EU now allows in most leave-on cosmetics under Regulation (EU) 2024/996. Great Britain had not adopted an equivalent limit when checked in September 2026.

## Who it’s for

A first retinol for readers who want a measured strength from a pharmacy skincare brand, with a gradual schedule written into the directions.

## What should you check before buying?

It contains fragrance and denatured alcohol — worth weighing if your skin is reactive, despite the sensitive-skin positioning. Use it in the evening only, follow the gradual start and wear SPF every morning. Speak to a pharmacist or GP before using retinoids in pregnancy.

## How to use it

1. Apply three drops in the evening, after cleansing
2. Use once or twice a week at first, building to five to seven evenings as tolerated
3. Follow with moisturiser
4. Use SPF every morning

## Questions and answers

### How strong is La Roche-Posay Retinol B3 Serum?

La Roche-Posay UK labels it 0.3% retinol, alongside niacinamide (vitamin B3).

### Does La Roche-Posay Retinol B3 Serum contain fragrance?

Yes. Parfum and denatured alcohol appear in the ingredient list.

### How often should I use La Roche-Posay Retinol B3 Serum?

The brand directs evening use once or twice a week at first, building up to five to seven evenings a week, with SPF in the morning.

## Explore the category

https://thecastindex.com/beauty/category/skin-prep