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The Cast Index

Medik8 · United Kingdom

C-Tetra

Skin prep · Vitamin C oil serum · Lightweight oil

A water-free vitamin C layer for morning prep — a fine oil to let settle before sunscreen and base.

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The desk verdict

A water-free vitamin C oil with 7% tetrahexyldecyl ascorbate and vitamin E, used in the morning before sunscreen, at £45. The derivative is stable but less studied than L-ascorbic acid, and grapefruit oil adds fragrance allergens.

Skip this if you want pure L-ascorbic acid, avoid fragrance allergens such as limonene and citral, or dislike oil textures in the morning.

The short version

The short version of this review

Medik8 C-Tetra is a lightweight, water-free vitamin C oil with 7% tetrahexyldecyl ascorbate and vitamin E, directed for morning use before sunscreen. It cost £45 for 30ml, or £15 for an 8ml travel size, on Medik8 UK on 25 September 2026. The formula contains grapefruit peel oil.

Product information reviewed 2026-09-25.

01 / The basics

What is C-Tetra?

Medik8 lists 7% tetrahexyldecyl ascorbate, an oil-soluble vitamin C derivative, with vitamin E in a lightweight oil; the brand directs four drops each morning after cleansing, then sunscreen, and a patch test 24 hours before first use. Grapefruit peel oil is in the formula.

Best for
A water-free morning vitamin C step

02 / Review

What is in C-Tetra?

C-Tetra uses tetrahexyldecyl ascorbate, an oil-soluble derivative of vitamin C, at 7% in a lightweight, water-free oil with vitamin E. Derivatives like this are more stable than L-ascorbic acid in the bottle, but there is less published evidence on how much becomes active vitamin C in skin.

Medik8 sells stronger siblings — C-Tetra Luxe at 14% and C-Tetra Advanced at 20% — built on the same derivative.

03 / Review

Who is C-Tetra best for?

Readers who prefer an oil texture in the morning, or who have found low-pH L-ascorbic acid serums uncomfortable, and anyone wanting a mid-priced first vitamin C with a travel size to try first.

04 / Review

What should you check before buying?

Despite the “no artificial fragrance” wording, grapefruit peel oil adds fragrance allergens — relevant for fragrance-sensitive skin. The 7% derivative is not directly comparable with 15% or 23% L-ascorbic acid. Let the oil settle before sunscreen so the layers do not slide.

05 / How to use it

How should you use C-Tetra?

  1. 01Patch test 24 hours before first use
  2. 02Apply four drops in the morning after cleansing
  3. 03Allow to settle, then apply sunscreen

06 / Quick facts

What should you know before choosing C-Tetra?

  • —7% tetrahexyldecyl ascorbate, an oil-soluble vitamin C derivative, with vitamin E
  • —Lightweight, water-free oil in a glass bottle with pipette
  • —£45 for 30ml, or £15 for an 8ml travel size, on Medik8 UK (25 September 2026)
  • —Morning use: four drops after cleansing, then sunscreen
  • —“No artificial fragrance”, but grapefruit peel oil and the fragrance allergens limonene, citral, linalool and geraniol are listed
  • —Patch test 24 hours before first use, per the brand

Further reading on The Cast Index

Facts on this page are drawn from the brand’s own product information and named, reputable press coverage, summarised in our own words. Inclusion in the Beauty Desk edit is editorial and independent of any commercial relationship. Last reviewed 2026-09-25. Corrections: desk@thecastindex.com.

FAQ

C-Tetra, answered

What is C-Tetra by Medik8?

C-Tetra is a vitamin c oil serum from Medik8, formulated for a water-free morning vitamin c step. Medik8 lists 7% tetrahexyldecyl ascorbate, an oil-soluble vitamin C derivative, with vitamin E in a lightweight oil; the brand directs four drops each morning after cleansing, then sunscreen, and a patch test 24 hours before first use. Grapefruit peel oil is in the formula.

Is Medik8 C-Tetra fragrance-free?

Not strictly. Medik8 says there is no artificial fragrance, but the ingredient list includes grapefruit peel oil and fragrance allergens such as limonene and citral.

What form of vitamin C is in Medik8 C-Tetra?

Tetrahexyldecyl ascorbate at 7%, an oil-soluble vitamin C derivative, with vitamin E.

Should I use Medik8 C-Tetra in the morning?

Yes. Medik8 directs four drops in the morning after cleansing, followed by sunscreen.

Also reviewed by the desk

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